Jinsi ya kuangalia hali ya joto ya wakati halisi kwa kutumia microwave ya radiofrequency katika hyperthermia ya tumor

Hyperthermia ya tumor ni nini

Tumor hyperthermia ni matumizi ya vyanzo mbalimbali vya joto kama vile mawimbi ya sumakuumeme ya radiofrequency, microwaves, au ultrasound ili kupasha joto eneo la uvimbe kwa kiwango cha joto cha matibabu na kudumisha kwa muda, kusababisha athari za metabolic mara moja katika tishu za tumor, na hivyo kusababisha mabadiliko katika muundo wa molekuli ya seli za tumor na kuimarisha shughuli za lysosomal, kufikia lengo la kuua seli za uvimbe na kutibu uvimbe.

The mfumo wa kipimo cha joto cha nyuzi za fluorescence iliyotengenezwa kwa kujitegemea na FJINO hutoa usaidizi wa kipimo cha joto kwa hyperthermia ya radiofrequency. Inaweza kupima joto kwa usahihi chini ya uwanja wa umeme wa radiofrequency kwa usahihi wa 1 ℃ (usahihi wa juu unaweza kubinafsishwa). Kwa kuchanganya simulation ya uwanja wa mafuta ya tishu za tumor, it is possible to infer the overall temperature distribution of the tumor through a few measurement points. After analyzing the experimental results and processing the data, it has been verified that the tumor radiofrequency hyperthermia device can meet the design requirements and has practical applications in the medical field.

Why does tumor hyperthermia require temperature measurement

Kwa sasa, all tumor extracorporeal radiofrequency hyperthermia machines on the market lack effective and feasible online monitoring methods for tumor temperature during tumor hyperthermia. Sensorer za joto za elektroniki za jadi, such as thermistors, thermocouples, nk., are susceptible to electromagnetic wave interference and cannot measure temperature in real time during the heating process, making it difficult to accurately determine the temperature of the tumor site and the normal tissue temperature around the tumor, seriously affecting the effectiveness of thermal therapy.

Compared with traditional temperature sensor measurement methods, optical waves have many incomparable advantages: light waves do not cause electromagnetic interference, nor are they interfered by electromagnetic waves, and are easily perceived and received by various photosensitive detectors. It is easy to convert optical signals into electrical signals or electrical signals into optical signals, which can be well matched with modern electronic devices and computers. The working spectrum of optical fibers is wide, the dynamic range is large, and it is an excellent transmission line with low loss. Fiber za macho wenyewe hazijashtakiwa au conductive, na utendaji mzuri wa insulation, radiation resistance, bendability, uzito mwepesi, and small volume. Wanaweza kutumika katika mazingira magumu ambapo aina nyingine za vitambuzi haziwezi kufikia masharti, kama vile vikwazo vikali vya nafasi, flammability, explosiveness, au kuingiliwa kwa nguvu kwa sumakuumeme.

Utaratibu wa kufanya kazi unaotumiwa katika kipimo cha joto cha fluorescence

Wakati nyenzo inasisimua kwa kufichua ultraviolet, inayoonekana, au mwanga wa infrared, jambo la utoaji wa mwanga huitwa photoluminescence. Katika uzushi wa photoluminescence, vigezo vya fluorescence iliyotolewa vinahusiana kwa karibu na joto la mazingira. Ili kupata habari inayohitajika ya joto, ni muhimu tu kuchunguza ukubwa au maisha ya fluorescence yake.

Mawasiliano kati ya maisha ya fluorescence na joto la fluorescence lifetime temperature sensors does not change due to changes in light intensity, and has advantages such as self calibration, small heat capacity, na kasi ya majibu ya haraka. The mfumo wa kipimo cha joto cha nyuzi za fluorescence can accurately measure temperature without interference under radio frequency electric fields;

Sensor ya joto ya fiber optic, Mfumo wa ufuatiliaji wa akili, Kusambazwa fiber optic mtengenezaji nchini China